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Application to join the ADCS

The ADCS conducts clinical trials in all phases of Alzheimer’s disease research from the pre-clinical phase, to mild cognitive impairment and dementia. A diagnosis is usually part of the entry criteria to our clinical trials. Therefore, the ADCS sites meet rigorous criteria in diagnosing the earliest stages of the disease, led by disease experts. These include neurologists, psychiatrists, or geriatricians, although other specialties may have this expertise as well.

Typical sites recruit from large practices treating community dwelling elders. These practices are often associated with memory clinics or other geriatric services. It is important to note that most trials require participants to have “study partners” who take part in the study procedures.

Many of our trials require that sites have the capacity to conduct biomarker studies which include sample and data collection from lumbar punctures and neuroimaging. The ADCS also uses distributed data entry so sites must have the capability to access the Internet in order to make electronic data submissions. In considering a new study site the ADCS evaluates the convenience and proximity to maximize data collection with these technologies.

Although a neuropsychologist is not required for all trials, it is important that there is a staff member who is capable of conducting cognitive tests. Outcome measures used in AD trials are often based on cognitive tests.

When new protocols are seeking sites we will announce them below, providing an application.